Protein_Domain
Part:BBa_K3522008:Design
Designed by: Kong Yangyang Group: iGEM20_NOFLS_YZ (2020-10-17)
RXRα
Assembly Compatibility:
- 10COMPATIBLE WITH RFC[10]
- 12COMPATIBLE WITH RFC[12]
- 21INCOMPATIBLE WITH RFC[21]Illegal BamHI site found at 705
Illegal BamHI site found at 858
Illegal BamHI site found at 972 - 23COMPATIBLE WITH RFC[23]
- 25INCOMPATIBLE WITH RFC[25]Illegal NgoMIV site found at 1270
Illegal AgeI site found at 558 - 1000COMPATIBLE WITH RFC[1000]
Design Notes
In order to meet the typeIIS standard, we made a synonymous mutation of Thr248Thr to remove BsaI restriction site.
Source
NDB stabilizes hFXRα homodimerization.